| Entry |
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| Name |
Aceclofenac (JAN/INN);
Aceclofenac (TN) |
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| Formula |
C16H13Cl2NO4
|
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| Exact mass |
353.0222
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| Mol weight |
354.1847
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| Structure |
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG01898 Anti-inflammatory drug, phenylacetic acid derivatives
|
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| Remark |
|
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| Efficacy |
Anti-inflammatory, COX inhibitor |
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| Target |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AB Acetic acid derivatives and related substances
M01AB16 Aceclofenac
D01545 Aceclofenac (JAN/INN)
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA25 Aceclofenac
D01545 Aceclofenac (JAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01906 Anti-inflammatory drug, acetic acid derivatives
DG01898 Anti-inflammatory drug, phenylacetic acid derivatives
D01545 Aceclofenac
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D01545 Aceclofenac (JAN/INN)
PTGS2 (COX2)
D01545 Aceclofenac (JAN/INN)
Isomerases (EC5)
Prostaglandin-E synthase
PTGES
D01545 Aceclofenac (JAN/INN)
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| Other DBs |
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| KCF data |
ATOM 23
1 C8x C 4.2700 -9.5900
2 C8x C 4.2700 -10.9900
3 C8y C 5.4824 -11.6900
4 C8y C 6.6949 -10.9900
5 C8y C 6.6949 -9.5900
6 C8x C 5.4824 -8.8900
7 N1b N 7.9260 -11.7010
8 C8y C 7.9257 -13.0899
9 X Cl 5.4824 -13.0898
10 X Cl 7.9260 -8.8790
11 C8x C 6.7014 -13.7966
12 C8x C 6.7012 -15.1966
13 C8x C 7.9135 -15.8967
14 C8x C 9.1379 -15.1901
15 C8y C 9.1381 -13.7901
16 C1b C 10.3743 -13.0762
17 C7a C 11.5819 -13.7733
18 O7a O 12.7631 -13.0912
19 O6a O 11.5824 -15.1896
20 C1b C 13.9576 -13.7809
21 C6a C 15.1454 -13.0951
22 O6a O 16.3365 -13.7829
23 O6a O 15.1455 -11.6902
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 3 9 1
10 5 10 1
11 8 11 2
12 11 12 1
13 12 13 2
14 13 14 1
15 14 15 2
16 8 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 17 19 2
21 18 20 1
22 20 21 1
23 21 22 1
24 21 23 2
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